Latest medical research – can cannabis treat edema? Learn the THC:CBD ratios. Try CannaKeys research tools. 1 Week Free Trial. 6 Things That Cause Fluid Retention in Your Body and How to Avoid Fluid retention, or edema, is caused by many things including 6 major factors. Not drinking enough water to flush out your system
Edema – Cannabis THC : CBD Ratios
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CannaKeys has 1 studies associated with Edema.
Here is a small sampling of Edema studies by title:
- Anti-Edema And Analgesic Properties of Δ9-Tetrahydrocannabinol (THC)
Components of the Edema Research Dashboard
- Dosing information available for Edema
- Chemotype guidance for treating Edema with cannabis
- Synopsis of cannabis research for Edema
- Individual study details for Edema
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Overview – Edema
Description of Edema
Edema is caused by the leakage and build-up of fluids from the capillaries (smallest blood vessels) and while it can occur in any part of the body it is usually worse (due to gravity )in those parts of the body closest to the ground such as ankles or feet for example. Underlying condition may include congestive heart failure, lymphatic blockages, liver disease, kidney failure, burns, pregnancy, or certain pharmaceutical medications (e.g. steroids, estrogen, non-steroidal anti-inflammatory drugs) for example. Orthodox treatment options in milder cases include elevation of affected limb, compression stockings, dietary changes (e.g. reduction of processed salts), upward stroking massage; and depending on underlying condition and in more severe cases involve the use of diuretics (aka water pills).
Organ System: Cardiovascular System, Integumentary System, Respiratory System
ICD-10 Chapter: Symptoms, signs and abnormal clinical and laboratory findings, not elsewhere classified
ICD-10 Code: R60
Swelling under the surface of the affected tissues, shinny stretched surface areas of the affected skin, pitting edema (any form of pressure will retain an imprint)
Also known as:
THC Interaction with Pharmaceutical Drugs
- THC can enhance the effects of drugs that cause sedation and depress the central nervous system, such as benzodiazepines, barbiturates, and alcohol, for example.
- THC is metabolized by and an inhibitor of a number of enzymatic liver pathways referred to as cytochrome P450. There are more than 50 enzymes belonging to this enzyme family, a number of which are responsible for the breakdown of common drugs such as antidepressants (e.g. amitriptyline, doxepine, fluvoxamine), antipsychotics (haloperidol, clozapine, stelazine), beta-blockers (e.g. propranolol), bronchodilators (e.g. theophylline), or bloodthinners (e.g. warfarin). Thus patients taking these classes of medication may find that THC increases the concentration and effects of these drugs as well as the duration of their effects.
- Clinical observation suggests no likely interactions with other pharmaceuticals at a total daily dose of up to 20mg THC.
CBD Interaction with Pharmaceutical Drugs
- CBD may alter action on metabolic enzymes (certain drug-transport mechanisms), and as such may alter interactions with other drugs, some of which may produce therapeutic or adverse effects. For instance, CBD interacts with the enzyme cytochrome P450 3A4 and cytochrome P450 2C19, increasing the bioavailability of anti-epileptic drugs such as clobazam (a benzodiazepine). This makes it possible to achieve the same results at significantly lower dosages, reducing treatment costs and risks of adverse effects.
- Groups of drugs affected include: anti-epileptic drugs, psychiatric drugs, and drugs affecting metabolic enzymes, for example.
- Clinical observations suggest no likely interactions with other pharmaceuticals at a total daily dose of up to 100mg CBD
THC Dosage Considerations
- THC micro dose: 0.1 mg to 0.4 mg (0.001mg/kg to 0.005mg/kg)
- THC low dose: 0.5 mg to 5 mg (0.006mg/kg to 0.06mg/kg)
- THC medium dose: 6 mg to 20 mg (0.08mg/kg to 0.27mg/kg)
- THC high dose: 21 mg to 50+ mg (0.28mg/kg to 0.67mg/kg)
CBD Dosage Considerations
- CBD low dose: 0.4 mg to 19 mg (0.005mg/kg to 0.25mg/kg)
- CBD medium dose: 20 mg to 99 mg (0.26mg/kg to 1.32mg/kg)
- CBD high dose: 100 mg to 800+ mg (1.33mg/kg to 10.7mg/kg)
- (upper limits tested ~1,500mg)
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Information on this site is based on scientific studies (human, animal, or in vitro), clinical experience, or traditional usage as cited in each article. The results reported may not necessarily occur in all individuals. For many of the conditions discussed, treatment with prescription or over-the-counter medication is also available. Consult your physician, nutritionally oriented health care practitioner, and/or pharmacist for any health problem and before using any supplements or before making any changes in prescribed medications.
6 Things That Cause Fluid Retention in Your Body and How to Avoid
Fluid retention, or edema, is caused by many things including 6 major factors. Not drinking enough water to flush out your system can cause retention – if you do not drink water, your body will then hold on to it (or retain it) to survive and keep organs functioning. Deficiencies of magnesium also cause water retention. Magnesium is a very important nutrient in our body and we need to intake at least 200 milligrams daily. Not doing so may lead to swelling. Not getting enough potassium may cause our organs to not function correctly and cause our bodies to hold on to water, since those very organs are what keep our water storage functioning.
While vitamin B6 may also cause water retention, reasoning as to why was not supplied in the article. Regardless, this can be avoided by eating certain foods rich in B6 vitamins.
Consuming too much salt also causes edema. If you eat too much without drinking water to flush it out of your system, you may hold on to that water weight. With that said, processed foods are often flavored with excessive salt and sugars, which our bodies aren’t meant to process. By consuming these things, your body is again getting too much of what it doesn’t need and in turn will retain water.
Finally, drinking water, or not enough, will also impact your body! The more water you drink, the less your body will hold on to. Drinking water flushes out your system and helps your body not retain, so everything runs smoother and theoretically functions correctly.
If retaining water, movement or exercise helps let go of those fluids. Also, elevating legs, eating more naturally occurring foods like fruits and vegetables, not wearing constricting clothes and avoiding hot showers all help in ridding ourselves of edema.
What causes fluid retention? #HealthStatus
- 1 Consuming too much sugar and salt is the main cause of water retention.
- 2 To combat fluid retention, eat foods high in magnesium such as avocado, spinach and whole grains.
- 3 Exercising helps decrease the amount of fluid in your body as it compresses the muscles in your veins.
Lack of potassium in the body may lead to improper functioning organs and fluid imbalance and retention as the mineral regulates the water balance in the body.
See the original at: https://cureandnature.com/2017/07/04/6-things-cause-fluid-retention-body-avoid/
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